Wales wing Josh Adams has been ruled out of the Six Nations trip to face Scotland in Murrayfield on Saturday.
Cardiff wing Adams, 29, missed the 27-18 defeat to Ireland in Cardiff and has not recovered in time for this weekend.
Gloucester fly-half Gareth Anscombe has recovered from a head knock suffered against Ireland and is available for selection.
Ospreys hooker Dewi Lake is also in contention for a return after missing the first three Six Nations defeats because of an arm injury.
Wales have lost a record 15 Test matches in a row with interim head coach Matt Sherratt taking over from Warren Gatland before the Ireland defeat.
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