Japanese world champion Naoya Inoue will defend his undisputed super-bantamweight title against Ramon Cardenas on 4 May at T-Mobile Arena in Las Vegas.
Inoue is a four-weight world champion and is yet to lose in 29 professional fights.
The 31-year-old, regarded as one of the best pound-for-pound fighters in the world, has not competed in America since 2021.
American Cardenas has recorded 26 wins in 27 fights and makes his first challenge for a world title.
“I am thankful to the fans in America who have followed my career. Fighting at T-Mobile Arena in Las Vegas is another career highlight,” Inoue said.
“Cardenas is a tough opponent who I respect for accepting the fight without hesitation.”
Inoue claimed a fourth-round stoppage victory against Ye Joon Kim in his last bout in January, after the South Korean stepped in on 11 days’ notice following the withdrawal of Sam Goodman.
He has only gone the distance on three occasions, with each of Inoue’s past 10 victories coming via stoppage.
The card will take place a day after another four-weight world champion, Saul ‘Canelo’ Alvarez – who holds the WBA ‘Super’, WBC and WBO super-middleweight titles – faces IBF super-middleweight champion William Scull in Riyadh, Saudi Arabia.
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