Premier League leaders Liverpool against defending French champions Paris St-Germain promises to be an intriguing tie.
PSG looked to be heading out of the competition before a late run of form saw them finish 15th in the league phase.
They lost to Arsenal before defeating Manchester City to set up an all-France knockout phase play-off with Brest which they won 10-0 on aggregate.
PSG have Ousmane Dembele who is one of the in-form goalscorers in Europe right now and has six goals in this season’s competition.
If Liverpool get past Luis Enrique’s side, then they will face Premier League rivals Aston Villa as long as they see off defending Belgian champions Club Brugge, who finished 24th in the league phase before defeating Atalanta in in the knockout phase play-offs.
However, Club Brugge beat Villa in the league phase, one of only two defeats suffered by Unai Emery’s side.
Arsenal’s opponents PSV Eindhoven are defending Dutch champions, who defeated an under-strength Liverpool side 3-2 in January on their way to finishing 14th in the league phase.
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